# Imperial College London

开发了 iKnife（智能刀），利用快速蒸发电离质谱（REIMS）实时分析电刀切割产生的气溶胶，根据其脂质组学特征识别组织类型，并已与 Waters Corporation 的质谱平台合作实现商业化。

Source: https://cn.bioecon.ru/companies/imperial-college-london/
Updated: 2026-07-20

- 国家: United Kingdom

## 可核验事实

| 事实 | 数值 | 来源 |
| --- | --- | --- |
| 隶属机构 | 生物分子医学部、CRUK交叉科学中心、癌症技术网络、临床表型分析中心、计算医学、分子科学与工程研究所、微生物组网络、国家表型组中心、帝国理工英国痴呆研究所、创面愈合与再生网络、Zoltan Takats课题组 | https://profiles.imperial.ac.uk/z.takats/about |
| 研究方向 | 质谱分析，特别是常压质谱与快速蒸发电离质谱（REIMS），用于术中实时组织诊断 | https://profiles.imperial.ac.uk/z.takats/about, https://www.imperial.ac.uk/news/126106/intelligent-knife-tells-surgeon-tissue-cancerous/, https://www.mdpi.com/2410-390X/10/1/9, https://www.queensu.ca/health-innovation/research/research-project-1/ |
| 实验设施 | 国家表型组中心、临床表型分析中心、帝国理工实验癌症医学中心、帝国理工NHS基金会信托（Charing Cross医院）、Sir Alexander Fleming大楼 | https://clinicaltrials.gov/study/NCT03432429, https://imperialbrc.nihr.ac.uk/2016/06/26/i-knife-for-breast-cancer-surgery/, https://imperialbrc.nihr.ac.uk/2016/06/29/validation-of-the-iknife/, https://phenomecentre.org/the-team/, https://profiles.imperial.ac.uk/z.takats/about, https://www.ecmcnetwork.org.uk/centres/london-imperial-college-london |
| 科研资助 | 欧洲研究理事会（Starting Grant与Proof-of-Concept Grant）、英国国家health与照护研究所（NIHR）、匈牙利国家研究与技术办公室、医学研究理事会Imperial Confidence in Concept计划、Waters Corporation研究经费 | https://erc.europa.eu/projects-statistics/science-stories/smart-knife-fight-cancer-crime-and-contamination, https://pmc.ncbi.nlm.nih.gov/articles/PMC7132269/, https://profiles.imperial.ac.uk/z.takats/about, https://spiral.imperial.ac.uk/entities/publication/4ccd36a0-370a-425a-a4da-4bd0f0ba818d, https://www.imperial.ac.uk/news/126106/intelligent-knife-tells-surgeon-tissue-cancerous/ |
| 论文产出 | 截至2012年初78篇同行评议论文 | https://profiles.imperial.ac.uk/z.takats/about |
| 主要研究人员 | Zoltan Takats（分析化学教授）、Ara Darzi（外科学教授）、Jeremy Nicholson（外科与肿瘤学系主任） | https://imperialbrc.nihr.ac.uk/2016/06/29/validation-of-the-iknife/, https://profiles.imperial.ac.uk/z.takats/about, https://www.imperial.ac.uk/news/126106/intelligent-knife-tells-surgeon-tissue-cancerous/, https://www.imperial.ac.uk/news/172586/iknife-showcased-nihr-10-year-celebration/ |
| 员工人数 | 专职研究人员（人数未披露） [中等置信度] | https://www.ecmcnetwork.org.uk/centres/london-imperial-college-london |

独立来源: clinicaltrials.gov, ecmcnetwork.org.uk, erc.europa.eu, imperialbrc.nihr.ac.uk, mdpi.com, phenomecentre.org, pmc.ncbi.nlm.nih.gov, profiles.imperial.ac.uk, queensu.ca, spiral.imperial.ac.uk

## 技术

- [术中分子诊断](https://cn.bioecon.ru/technology/intraoperative-molecular-diagnostics/)